Studies on experimentally produced acute hypoferremia in dogs and the relationship of the adrenal cortex to hypoferremia. Year Book Publishers, Chicago 1952.Ĭartwright, G. Studies on the iron-binding capacity of serum. M.: Chemical, clinical and immunological studies on the products of human plasma fractionation. et al.: Haem biosynthesis in rheumatoid disease. et al.: Iron-binding proteins and infection. Grune and Stratton, New York 1956.īullen, J. V.: Parenterally administered iron in the treatment of hypochromic anemia. S.: Serumeisen bei akuten und chronischen Infektionen. Heilmeyer, 1964.īesta, B., Valenti, S.: L’anemia tubercolare: patogenesi, clinica e terapia.
C., Breton-Gorius, J.: Iron metabolism in the bone marrow as seen by electron microscopy: A critical review. A.: The diagnosis of iron deficiency anemia. This process is experimental and the keywords may be updated as the learning algorithm improves.Īndersson, N. These keywords were added by machine and not by the authors. An increased reticulocyte count is exceptional. The number of reticulocytes is diminished or normal (Cartwright et al., 1946, 1951, 1954). Anisocytosis and poikilocytosis are not conspicuous, and signs of bone marrow regeneration such as polychromatophilia or the presence of nucleated red cells in the blood are absent. Hypochromia of the degree seen in iron-deficiency disease is unusual. In general, it is normochromic or slightly hypochromic, the PCV is seldom less than 30%, and the mean hemoglobin concentration of the red cells usually ranges between 28 and 32%. Bacterial infections or conditions associated with severe sepsis may produce a fairly severe anemia of rapid onset, but the anemia of chronic disorders is usually not severe or progressive (Cartwright, 1966 Cartwright and Lee, 1971). Infections, particularly chronic infections, are frequently associated with anemia.